Kava (Piper mythysticum) was historically consumed during Polynesian religious rites for its ability to relax and soothe the mind. Kava was also used for its medicinal effects including as a sedative. In an experimental double-blind study, 58 patients received either Kava extract (100 mg. t.i.d.) or a placebo over a four week period. The Hamilton-Anxiety scale overall score of anxiety and other anxiety scales revealed a significant reduction in the group receiving the kava extract. No adverse effects were noted. Kava has recently become available as an herbal supplement
Arzneim Forsche 41 (6) 584-8 1991